Increasing Thyromimetic Potency through Halogen Substitution
نویسندگان
چکیده
منابع مشابه
Halogen transfer through halogen bonds in halogen-bound ammonia homodimers.
Ab initio MP2(full)/aug-cc-pVTZ calculations have been carried out to investigate the halogen transfer between haloamines and ammonia. The results show that the formation of a halogen bond complex between ammonia and the protonated N-haloamine is a preliminary step in the halogen transfer process. The complexation energies, optimized geometries, topology of electron density and potential energy...
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The ultraviolet absorption spectra of uracil and its 5-halogenated derivatives have been in vestigated in regard to the electron attracting properties of the substituents. It could be shown that the position of the two absorption bands is proportional to the inverse of the electronegativity; the extinction coefficients are a linear function of the electron affinities. In this way, the red shif...
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ژورنال
عنوان ژورنال: ChemMedChem
سال: 2016
ISSN: 1860-7179
DOI: 10.1002/cmdc.201600408